Publications

  1. Roberts, C., Chaput, J.C. and Switzer, C. 1998. Beyond Guanine Quartets: Cation-Induced Formation of Homogeneous and Chimeric DNA Tetraplexes Incorporating iso-Guanine and Guanine. Chemistry & Biology 4, 899-908.
  2. Chaput, J.C. and Switzer, C. 1999. A DNA Pentaplex Incorporating Nucleobase Quintets. Proc. Natl. Acad. Sci. USA 96, 10614-10619.
    Commentary by Stu Borman Featured in Chemical & Engineering News. Science & Technology Concentrate: First DNA Pentaplex., Sept. 27, 1999, p.28.
  3. Rice, K.P., Chaput, J.C., Cox, M.M. and Switzer, C. 2000. RecA Protein Promotes Strand Exchange with DNA Substrates Containing isoGuanine and 5-Methyl isoCytosine. Biochemistry 39, 10177-10188.
  4. Chaput, J.C. and Switzer, C. 2000. Non-enzymatic Oligomerization on Templates Containing Phosphodiester-Linked Acyclic Glycerol Nucleic Acid Analogues. J. Mol. Evol. 51, 464-470.
  5. Chaput, J.C. and Switzer, C. 2000. Non-enzymatic Transcription of an isoG:isoC Base Pair. J. Am. Chem. Soc. 122, 12866-12867.
  6. Chaput, J.C. and Switzer, C. 2001. Probing DNA Structure and Function with Alternative Nucleic Acids Bearing 2’,5’-Linked, Zwitterionic and iso-Cytosine iso-Guanine Components. Methods: A Compendium to Methods in Enzymology 23, 141-148.
  7. Chaput, J.C., Sinha, S. and Switzer, C. 2002. 5-Propynyluracil diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA. Chem. Comm. 1568-1569.
  8. Chaput, J.C., Ichida, J.K. and Szostak, J.W. 2003. DNA Polymerase-Mediated DNA Synthesis on a TNA Template. J. Am. Chem. Soc. 125, 856-857.
    Commentary by Celia Henry Featured in Chemical & Engineering News. Article: DNA Synthesized from TNA Template. Jan. 13, 2003, p.9.
  9. Chaput, J.C. and Szostak, J.W. 2003. DNA Polymerase-Mediated TNA Synthesis. J. Am. Chem. Soc. 125, 9274-9275.
  10. Chaput, J.C. and Szostak, J.W. 2004. Evolutionary Optimization of a Non-Biological ATP-Binding Protein for Improved Folding Stability. Chemistry & Biology. 11, 865-874.
  11. Horhota, A., Keyong, Z., Ichida, J.K., McLaughlin, L.W., Szostak, J.W. and Chaput, J.C. 2005. Kinetic Analysis of an Efficient DNA-Dependent TNA Polymerase. J. Am. Chem. Soc. 127, 7427-7434.
  12. Nilsson, M., Stomel, J., and Chaput, J.C. 2005. Evolutionary Optimization of a De Novo Selected ATP Binding Protein. Biopolymers 80, 592.
  13. Williams, B.A.R., Lund, K., Liu, Y., Yan, H. and Chaput, J.C. 2006. Self-Assembled Peptide Nanoarrays: A New Approach to Studying Protein-Protein Interactions. Agnew. Chem. Int. Ed., In press.
  14. Yang, Y-W., Zhang, S., McCullum, E., and Chaput, J.C. 2006. Investigation into the Origins of the RNA World. Submitted.
  15. Mansy, S.S., Zhang, J., Kuemmerle, R., Nilsson, M., Chou, J.J., Szostak, J.W., and Chaput, J.C. 2006. Structure and Evolutionary Analysis of a Non-Biological ATP Binding Protein. Submitted.
  16. Smith, M., Rosenow, M, Szostak, J.W., Allen, J. and Chaput, J.C. 2006. Evolutionary Optimization of a Non-biological Protein Reveals a Surprising New Role for Surface Residues. In Preparation.
  17. Diehnelt, C., Williams, B.A.R., Chaput, J.C., and Johnston, S.A. 2006. A Chemical Approach to Synthetic Antibodies. In Preparation.