Mor

Mor Lab: Publications

photo of plants in a green houseA note on the significance of the author list order: Last author position is usually reserved to the author of correspondence who is responsible of the research design and manuscript writing and its final form. The first author posi tion in the case of primary research publications is reserved to the person most intimately connected with carrying out the experiments and drafting the manuscr ipt. In review articles, the first author is usually the person who most substan tially contributed to the writing of the manuscript. Middle authors usually cont ributed to the research by carrying out some of the experiments or substantially assisting in the experiments, intellectual input, experimental design etc.

An asterisk (*) denotes members of the Mor lab. A dag ger (†) denotes the author of correspondence.

Journal Articles:

  • Evron T, Greenberg D, Mor TS and †Soreq H. Adaptive changes in acetylcholinesterase gene expression as mediators of recovery from chemical and biological insults. Toxicology (in pr ess)
  • *Matoba N, *Geyer BC, *Kilbourne J, Alfsen A , Bomsel M and †Mor TS (2006) Humoral immune responses b y prime–boost heterologous route immunizations with CTB–MPR649– ;684, a mucosal subunit HIV/AIDS vaccine candidate. Vaccine 24:5047–5055
  • Saldaña S, Guadarrama FE, de Jes&uacu te;s Olivera Flores T, Arias N, López S, Arias C, Ruiz R, Mason H, Mor T, Richter L, Arntzen CJ and Gómez Lim MA. (2006) Production of rotavirus&n dash;like–particles in tomato (Lycopersicon esculentum L.) fruit by expres sion of capsid proteins VP2 and VP6 and immunological studies. Viral Immunol 19: 42–53
  • *Geyer BC, *Muralidharan M, *Cherni I, *Dora n J, *Fletcher SP, Evron, T, Soreq H and †Mor TS (2005) Purification of Transgenic Plant–Derived Recombinant Human Acetylcholinest erase–R. Chem Biol Interact 157–158:406–407
  • *Muralidharan M, Soreq H and †Mor, TS (2005) Characterizing Pea Acetylcholinesterase. Chem Biol Interact 157–15 8:331–334
  • *Matoba N, Magérus A, *Geyer BC, Zhan g Y, *Muralidharan M, Alfsen A, Arntzen CJ, Bomsel M and †Mor TS< /strong> (2004) Mucosally–targeted subunit vaccine candidate eliciting HIV –1 transcytosis–blocking antibodies. Proc Natl Acad Sci USA 101:1358 4–13589
  • *Fletcher SP, *Geyer BC, Smith A, Evron T, J oshi L, Soreq H and †Mor TS (2004) Tissue distribution o f cholinesterases and anticholinesterases in native and transgenic tomato plants . Plant Mol Biol 55:33–44
  • Mor TS, Moon Y–S, Pal mer, KE and †Mason, HS (2003) Geminivirus vectors for high level expressi on of foreign proteins in plant cells. Biotechnol Bioeng 81: 430–437
  • Mason HS, Warzecha H, Mor T and †Arnt zen CJ (2002) Edible plant vaccines: applications for prophylactic and therapeut ic molecular medicine, Trends Mol Med 8, 324–9
  • †Mor TS, Sternfeld M , Arntzen CJ, Soreq H and Mason, HS (2001) Expression of recombinant human acety lcholinesterase in transgenic tomato plants. Biotechnol Bioeng 75:259–266< /li>
  • †Mor TS, Góme z–Lim MA and Palmer, KE (1998) Edible plant vaccines: A concept coming of age. Trends Microbiol 6:449–453
  • Mor TS, Hundal T, †O had I and †Andersson B (1997) The fate of cytochrome b559 during anaerobi c photoinhibition and its recovery processes Photosynth Res 53:205–213
  • Mor TS, Ohad I, Hirschberg J and †Pakrasi HB (1995) An unusual organization of the genes encoding cy tocrhome b559 in Chlamydomonas reinhardtii: psbE and psbF genes are separately t ranscribed from different regions of the plastid chromosome. Mol Gen Genet 246:6 00–604
  • Anbudurai PA, Mor TS, Ohad I, Shestakov SV and †Pakrasi HB (1994) The ctpA gene encodes the c– terminal processing protease for the D1 of the photosystem II reaction center co mplex Proc Natl Acad Sci USA 91:8082–8086
  • Mor TS, Post AF and † ;Ohad I (1993) The Manganese stabilizing protein (MSP) of Prochlorothrix holland ica is a hydrophobic membrane bound protein Biochim Biophys Acta 1141:206– 212


Book Chapters:

  • *Matoba N and †Mor TS (2005) Plant–derived subunit vaccines, In Plant Genetic Engineering Vol. 7 B: Metabolic Engineering & Molecular Pharming (Jaiwal PK, Ed) pp 143&ndas h;183. Studium Press, Houston
  • †Mor TS, Mason HS, K irk DD, Arntzen CJ and Cardineau GA (2004) Plants as a production and delivery v ehicle for orally delivered subunit vaccines. In Current Vaccines 3rd Edition (L evine M, Ed) pp 305–312, Marcel Dekker, New York
  • †Mor TS and Mason HS (2004) Transgenic plants as a source for subunit vaccines. In: Handbook of Plan t Biotechnology (Christou P and Klee H, Eds) pp 768–780, John Wiley & Sons Ltd, West Sussex
  • †Mor TS and Soreq H (2004) Human cholinesterases from plants for detoxification. In Encyclopedia of Plant & Crop Science (Goodman RM, Ed) pp 564–567, Marcel Dekker, New Y ork
  • Mor TS and †Arntzen CJ (2003) Plants and Human Health: Delivery of vaccines via transgenic plants. I n Plant Biotechnology 2002 and Beyond (Vasil, JK, Ed) pp 383–387, Kluwer A cademic Publishers, Dordrecht
  • Mor TS, Richter, L and &dag ger;Mason HS (1999) Expression of rotavirus proteins in transgenic plants. In Pl ant Biotechnology and In–Vitro Biology in the 21st Century (Alt man A, Ziv M and Izhar S, Eds) pp 521–524, Kluwer Academic Publishers, Dor drecht
  • Mor TS and †Arntzen CJ (1999) Pharmaceutical foodstuffs: oral immunization with transgenic plants. I n Plant Biotechnology and In–Vitro Biology in the 21st Century (Altman A, Ziv M and Izhar S, Eds) pp 17–20, Kluwer Academic Publishers, D ordrecht
  • Domovich Y, Mor TS, Oetmüll er R, Herrman RG and †Ohad I (1995) Reversible dissociation of the OEC pr oteins from the lumenal side of the thylakoid membrane during photoinhibition an d recovery. In Photosynthesis: From Light to Biosphere (Mathis P, Ed) Vol IV, pp 311–314, Kluwer Academic Publishers, Dordrecht
  • Mor TS, Pakrasi HB and &dag ger;Ohad I (1995) The impact of the F26S mutation in the β subunit of cytochrome b559 on the function and stability of photosystem II in tobacco. In Photosynthe sis: From Light to Biosphere (Mathis P, Ed) Vol I, pp 927–930, Kluwer Acad emic Publishers, Dordrecht
  • †Ohad I, Keren N, Zer H, Gong H, Mor TS, Gal A, Tal S and Domovitch Y (1993) Light induced degradati on of the photochemical reaction center II D1 protein in–vivo: An integrat ive approach. In The Proceedings of the 41st Harden Conference on Photoinhibitio n of Photosynthesis From Molecular Mechanisms to the Field (Baker NR and Bowyer JR, Eds) pp 161–171, Bios Scientific Publishers, Oxford
  • Mor TS, Post, A F, and &dag ger;Ohad I (1991) Prochlorothrix hollandica is more sensitive to photoinhibition than Chlamydonomans reinhardtii. In Regulation of Chloroplast Biogenesis (Argyr oudi–Akoyunoglou JH, Ed) pp 433–438, Plenum Press, New York
  • Mor TS, Post, A F, and &dag ger;Ohad I (1991) Characterization of the oxygen evolving system of Prochlorothr ix hollandica. In Regulation of Chloroplast Biogenesis (Argyroudi–Akoyunog lou JH, Ed) pp 427–432, Plenum Press, New York
  • Gal, A, Mor TS, Hauska, G, Herrmann, R and †Ohad I (1990) LHCII kinase activity associated with Isol ated Cytochrome b6/f complex. In Current Research in Photosynthesis (Baltscheffs ki M, Ed) Vol I pp 783–785, Kluver Academic Publishers, Dordrecht

Thesis:

  • Mor TS (1996) Dynamics of Photosystem II: Structural and Functional Aspects of Proteins Associated with the Reaction Center. Academon Press, Jerusalem


Abstracts (Since 2002, Partial List)

  • *Cherni, I, *Geyer BC, *Matoba N and Mor TS. MPR649–684–HBsAg Fusion as a Vaccine Ca ndidate against HIV–I Infection. International AIDS Vaccine 2006 Conferenc e, Amsterdam, The Netherlands, August 29 – September 1, 2006
  • *Geyer BC and Ben–Ari, S *Cherni I, Ev ron E, Soreq H and Mor TS. Preventable Induction of Muscle Alte rnative Splicing in Organophosphate–Exposed Mice Treated with Recombinant Human Acetylcholinesterase. Genomes, Evolution, & Bioinformatics (GEB2006), Tempe, Arizona, May 24–May 28, 2006
  • *Chelladurai SA, Muralidharan M, and Mor, TS . Gene expression analysis for cholinesterase homologs in plants Genomes, Evolut ion, & Bioinformatics (GEB2006), Tempe, Arizona, May 24–May 28, 2006
  • *Muralidharan M, Soreq H and Mor, TS. Charac terizing a cholinesterase homologue in plants. Genomes, Evolution, & Bioinfo rmatics (GEB2006), Tempe, Arizona, May 24–May 28, 2006
  • *Geyer BC and Evron E, *Cherni I, *Muralidha ran M, *Kilbourne J, *Fletcher SP, Soreq H and Mor TS. Plant&nd ash;Derived Human Acetylcholinesterase–R provides protection from lethal o rganophosphate poisoning and its chronic aftermath. Bioscience Medical Defense R eview 2006 (The U.S. Army Medical Research Institute of Chemical Defense), Hunt Valley, MD, June 4–9 2006
  • *Matoba N, Magérus A, *Geyer BC, Alfs en A, Hanson CV, Arntzen CJ, Bomsel M and Mor TS. Humoral immun ity induced by CTB–MPR649–684 towards the prevention of HIV–1 mucosal transmission/infection”. 12th International Congress of Mucosal Immunolo gy, Boston, MA, June 24 – 30, 2005
  • *Matoba M, Magerus A, *Geyer BC, *Zhang Y, A lfsen A, Arntzen CJ, Bomsel M and Mor TS. Towards an oral plant –derived HIV–1 subunit vaccine. Plant–Based Vaccines & Ant ibodies. PBVA 2005, Prague, Czech Republic, June 8–10, 2005. Selected for oral presentation (Mor)
  • *Matoba M, Magerus A, *Geyer BC, Alfsen A, A rntzen CJ, Bomsel M and Mor TS (2005) Humoral immunity induced by CTB–P1 for the Prevention of HIV–1 Mucosal Transmission/infection . Plant–Based Vaccines & Antibodies. PBVA 2005, Prague, Czech Republic , June 8–10, 2005 Selected for oral presentation (Matoba)
  • *Geyer BC, Evron T, *Cherni I, *Muralidharan M, *Patel A, *Fletcher S, Soreq H and Mor TS (2005) N. bentham iana Produced Human Acetylcholinesterase Completely Protects Mice from Lethal Do ses of Organophosphate Toxins. Annual Meeting of the American Society of Plant B iologists, Seattle, Washington, July 16–20, 2005
  • *Matoba M, Magerus A, *Geyer BC, *Zhang Y, A lfsen A, Arntzen CJ, Bomsel M and Mor TS. Towards an oral plant –derived HIV–1 subunit vaccine. HIV Vaccine Development: Progress an d Prospects, Keystone Symposium, Banff, AB, Canada, April 9–15, 2005.
  • *Matoba M, Magerus A, *Geyer BC, *Zhang Y, * Alfsen A, Arntzen CJ, Bomsel M and Mor TS. Humoral immunity ind uced by CTB–P1 for the Prevention of HIV–1 Mucosal Transmission/infe ction. HIV Vaccine Development: Progress and Prospects, Keystone Symposium, Banf f, AB, Canada, April 9–15, 2005.
  • *Muralidharan, M, *Fletcher, SP, *Geyer, BC, Soreq, H and Mor TS (2004) Characterizing pea acetylcholineste rase. VIIIth International Meeting on Cholinesterases, Perugia, Italy, September 26–30, 2004
  • *Matoba N, Mor TS and Arntz en CJ (2004) Heat–stable oral vaccines from transgenic plants. Pharmaceuti cal Sciences World Congress 2004, Kyoto, Japan, May 30–June 3, 2004. (Invi ted talk, Matoba)
  • *Fletcher SP, *Geyer B, *Muralidharan M, Arn tzen CJ, Soreq H and Mor TS (2004) Chemical warfare countermeas ures: Expression of human acetylcholinesterase in plants. Gordon Research Confer ence in Plant Molecular Biology, Plymouth, New Hampshire, July 18–23, 2004 .
  • *Matoba M, Magerus A, *Geyer BC, *Zhang Y, A lfsen A, *Arntzen CJ, Bomsel M and Mor TS (2004) A subunit vacc ine candidate to prevent HIV–1 transmission. HIV Vaccine Development: Prog ress and Prospects, Keystone Symposium, Whistler, BC, Canada, April 10–15, 2004
  • *Fletcher SP, *Geyer B, *Muralidharan M, Jos hi L, Soreq H and Mor TS (2003) Transgenic plants expressing hu man acetylcholinesterase: what they may do for us and what we may learn from the m. ISPMB Congress 2003:S26–20. International Congress of Plant Molecular B iology, Barcelona, Spain, June 23–28, 2003
  • *Fletcher SP, *Geyer B, *Muralidharan M, Arn tzen CJ, Soreq H and Mor TS (2003) Chemical warfare countermeas ures: Expression of human acetylcholinesterase in plants. In–vitro Cell De v Biol Plant 39:28–A. Congress on in vitro Biology, Portland, Oregon, May 31–June 04, 2003. Selected for oral presentation (Fletcher)
  • *Matoba N, Bomsel M, Arntzen CJ and Mor TS (2003) Towards a mucosal vaccine against HIV. In–vitro Cel l Dev Biol Plant 39:23–A. Congress on in vitro Biology, Portland, Oregon, May 31–June 04, 2003. – chosen for oral presentation
  • *Fletcher SP, *Geyer B, Soreq H and Mor TS (2002) Acetylcholinesterase and plants: An inquiry to plant bioc hemistry and a biotechnology application. Plant Physiol (Rockville) 2002:182. An nual Meeting of the American Society of Plant Biologists on Plant Biology Denver , Colorado, August 3–7, 2002
  • *Muralidharan M, *Geyer B, Soreq H and Mor TS (2002) Role for acetylcholinesterase in gravitropic responses . Plant Physiol (Rockville) 2002:114. Annual Meeting of the American Society of Plant Biologists on Plant Biology, Denver, Colorado, August 3–7, 2002


Manuscripts Undergoing Revision

  • *Fletcher SP, *Geyer BC, *Griffin TA, *Lopke r MJ, Soreq H and †Mor, TS. Translational control of recombinant human ac etylcholinesterase accumulation in plants. To be submitted to BMC biotechnology.
  • Evron T,^*Geyer BC, *Cherni I, *Muralidharan M, *Fletcher SP, Soreq H and †Mor TS. Plant–Deriv ed Human Acetylcholinesterase–R provides protection from lethal organophos phate poisoning and its chronic aftermath. To be submitted to PNAS
  • Mor I, Sklan EH, Podoly E, Pick M, Kirschner M, Yogev L, Schreiber L, *Geyer BC, Mor TS, Grisaru D and &dag ger;Soreq H. Interchanging AChE interactions with RACK1 and enolase provide dual selection advantage to male germ cells. To be submitted to Molecular Cell.
  • Manuscripts in Preparation
  • *Cherni I, *Geyer BC, Wang K and Mor TS Expression of recombinant acetylcholinesterase in maize. (figures, draft–text) Biotechnology Progress
  • *Woods, RR, *Geyer BC and Mor, TS. Productio n of recombinant human acetylcholinesterase in hairy root cultures. (figures) To be submitted to Plant Biotechnology Journal.
  • *Matoba N, *Mittman M, *Griffin TA, *Cherni I, *Alfsen A, Bomsel M and Mor, TS. Comparative analysis of a mucosal HIV vaccin e candidate CTB–MPR649–684 expressed in E. coli and N. benthamiana T o be submitted to J Mol Biol
  • *Matoba N, *Griffin TA, *Cherni I, *Kilbourn e J, Alfsen A, Bomsel M and Mor TS. Oral immunogenicity of a mu cosal HIVvaccine candidate CTB–MPR649–684 expressed in tomato. To be submitted to Plant Biotechnol J.
  • *Geyer, BC, Ben–Ari S, Soreq H and Mor TS. Global changes in alternative splicing associated with org anophosphate poisoning and acetylcholinesterase therapy. (most figures, statisti cal analysis still on going) Biochemical Pharmacology
  • *Geyer BC, *Delisle J, … Soreq H and Mor TS. The “readthrough” variant of acetylcholinesterase directs acetylcholinesterase transcription in skeletal muscle via a TNF–al pha/NF–kB–dependent mechanism. (Some figures ready, experiments stil l on–going) JBC