Biodesign Directory Profile

Selected Publications

2007

• Ye, Y, Hauns, K, Langland, J O, Jacobs, Bertram Lewis, Hogue, B G. Mouse Hepatitis Coronavirus A59 Nucleocapsid Protein is a Type I Interferon Antagonist. J Virol (2007).

2006

• Langland, J O, Cameron, J M, Heck, M C, Jancovich, J K, Jacobs, Bertram Lewis. Inhibition of PKR by RNA and DNA viruses. (2006).
• Langland, J O, Kash, J C, Carter, V, Thomas, M J, Katze, M G, Jacobs, Bertram Lewis. Suppression of proinflammatory signal transduction and gene expression by the dual nucleic acid binding domains of the vaccinia virus E3L proteins. J Virol (2006).
• Langland, Jeffrey O, Cameron, Jason M, Heck, Michael C, Jancovich, James K, Jacobs, Bertram Lewis. Inhibition of PKR by RNA and DNA viruses. Virus Research (2006).

2005

• Brandt, T, Heck, M C, Vijaysri, S, Jentarra, G M, Cameron, J M, Jacobs, Bertram Lewis. The N-terminal domain of the vaccinia virus E3L-protein is required for neurovirulence, but not induction of a protective immune response. Virology (2005).
• Jancovich, J K, Davidson, E W, Parameswaran, N, Mao, J, Chinchar, V G, Collins, J P, Jacobs, Bertram Lewis, Storfer, A. Evidence for emergence of an amphibian iridoviral disease because of human-enhanced spread. Mol Ecol (2005).

2004

• Auch, C J, Saha, R N, Sheikh, F G, Liu, X, Jacobs, Bertram Lewis, Pahan, K. Role of protein kinase R in double-stranded RNA-induced expression of nitric oxide synthase in human astroglia. FEBS Lett (2004).
• Kibler, K V, Miyazato, A, Yedavalli, V S, Dayton, A I, Jacobs, Bertram Lewis, Dapolito, G, Kim, S J, Jeang, K T. Polyarginine Inhibits gp160 Processing by Furin and Suppresses Productive Human Immunodeficiency Virus Type 1 Infection. J Biol Chem (2004).
• Langland, J O, Jacobs, Bertram Lewis. Inhibition of PKR by vaccinia virus: role of the N- and C-terminal domains of E3L. Virology (2004).

2003

• Jancovich, J K, Mao, J, Chinchar, V G, Wyatt, C, Case, S T, Kumar, S, Valente, G, Subramanian, S, Davidson, E W, Collins, James, Jacobs, Bertram Lewis. Genomic sequence of a ranavirus (family Iridoviridae) associated with salamander mortalities in North America. Virology (2003).
• Jancovich, J K, Mao, J, Chinchar, V G, Wyatt, C, Case, S T, Kumar, Sudhir, Valente, G, Subramanian, S, Davidson, E W, Collind, J P, Jacobs, Bertram Lewis. Genomic Sequence of a Ranavirus (Family Iridoviridae) Associated with Salamander Mortalities in North America. Virology (2003).
• Kim, Y G, Muralinath, M, Brandt, T, Pearcy, M, Hauns, K, Lowenhaupt, K, Jacobs, Bertram Lewis, Rich, A. A role for Z-DNA binding in vaccinia virus pathogenesis. Proc Natl Acad Sci U S A (2003).
• Langland, J O, Kao, P, Jacobs, Bertram Lewis. Regulation of IL-2 gene expression and nuclear factor-90 translocation in vaccinia virus-infected cells. J Interferon Cytokine Res (2003).
• Vijaysri, S, Talasela, L, Mercer, A A, McInnes, C J, Jacobs, Bertram Lewis, Langland, J O. The Orf virus E3L homologue is able to complement deletion of the vaccinia virus E3L gene in vitro but not in vivo. Virology (2003).

2002

• He, Y, Nakao, H, Tan, S L, Polyak, S J, Neddermann, P, Vijaysri, S, Jacobs, Bertram Lewis, Katze, M G. Subversion of cell signaling pathways by hepatitis C virus nonstructural 5A protein via interaction with Grb2 and P85 phosphatidylinositol 3-kinase. J Virol (2002).
• Langland, J, Jacobs, Bertram Lewis. The Role of the PKR-Inhibitory Genes, E3L and K3L, in Determining Vaccinia Virus Host Range. Virology (2002).
• Xiang, Y, Condit, R C, Vijaysri, S, Jacobs, Bertram Lewis, Williams, B R, Silverman, R H. Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus. J Virol (2002).

2001

• Brandt, T A, Jacobs, Bertram Lewis. Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model. J Virol (2001).
• He, Y, Tan, S L, Tareen, S U, Jacobs, Bertram Lewis, Vijaysri, S, Langland, J O, Katze, M G. Regulation of mRNA translation and cellular signaling by hepatitis C virus nonstructural protein NS5A. J Virol (2001).